The Henderson County Joint Task Force along with Kentucky State Police executed a search warrant on N. Adams Street on Wednesday.
Police found around three pounds of marijuana, over a pound of magic mushrooms, ecstasy pills, one handgun, and other evidence.
Two children under the age of 4 were inside the residence, as well.
Tyrone Williams was arrested and was found to have over 10 previous felony convictions spanning four states.
Stanley Ward was arrested and was found to have 7 previous felony convictions spanning five states.
They are both in the Henderson County Jail.